The problem of serious mental illness is a widely discussed topic in the media and popular culture. This text provides a comprehensive analysis of antipsychotic medications, covering historical, social, and scientific viewpoints on this important and controversial class of medications.Antipsychotics are unique drugs with the ability to alter how people think and communicate. As a result, physicians must weigh a range of implications when prescribing antipsychotics. Antipsychotics: History, Science, and Issues offers a robust explanation of antipsychotic medications that covers the historical, ethical, medical, legal, and scientific dimensions of antipsychotics. The chapters explore topics ranging from the science of how examples of this class of drug actually work in the body to the social and legal implications of antipsychotics, making this subject understandable and relatable for lay readers who are not mental health practitioners. Readers will learn why prescribing antipsychotics is often a difficult decision due to the inherent risks of giving these medications to different types of patients and appreciate how mental health laws impact psychiatrists'prescribing practices.

motw/Antipsychotics_ History, Scienc - Jeffrey Kerner.epub

motw/Antipsychotics_ History, Scienc - Jeffrey Kerner.pdf

Kerner, Jeffrey, McCoy M.D., Bridget

Greenwood Publishing Group, Incorporated

Greenwood; Bloomsbury

Praeger

Story of a drug, Santa Barbara, California, 2017

United States, United States of America

The Story of a Drug Series, 2017

Jan 26, 2017

2017-01-26

producers:
Adobe Acrobat 8.1; modified using iTextSharpTM 5.5.2 ©2000-2014 iText Group NV (AGPL-version)

Memory of the World Librarian: Slowrotation

Source title: Antipsychotics: History, Science, and Issues (Story of a Drug)

Cover 1
Half Title 2
Title Page 4
Copyright 5
Contents 6
Series Foreword 10
Acknowledgments 12
Introduction 14
Chapter 1: Case Studies 18
Case 1: Jimmy 18
Case 2: Bobby 24
Case 3: George 31
Chapter 2: What Are Antipsychotics? 36
Psychotic Disorders and the Symptoms of Psychosis 36
Treatment of Psychosis: From Exorcism to Antipsychotics 42
Typical Antipsychotics: The Beginning 45
Atypical Antipsychotics: As the Story Continues. . . 59
Chapter 3: Antipsychotics: A Brief History 68
Early Biologic Remedies: The Original Antipsychotics 70
“A Drug in Search of an Illness”: Developing Antipsychotic Medications 74
Chlorpromazine Rises 77
Side Effects Emerge 81
Competition for Chlorpromazine 82
How Antipsychotics Are Used Today: Bridging Past and Future 86
Chapter 4: How Antipsychotics Work 90
Parts of the Brain 91
What Are Neurotransmitters and What Do They Do? 93
Neurotransmitters Affected by Antipsychotics 94
Other Potential Targets 108
Chapter 5: Effects and Applications 110
Therapeutic Effects of Antipsychotics 110
How Well Do Antipsychotics Work? 120
Indications for Medical Use 124
Antipsychotic Use in Special Groups 134
Chapter 6: Risks, Misuse, and Overdose 140
Side Effects 140
Misuse of Antipsychotics 164
Antipsychotic Overdose and Toxicity 165
Chapter 7: Production, Distribution, and Regulation 168
Pharmaceutical Industry 168
Antipsychotics in Nursing Homes 176
Prior Authorization 177
The Unique Case of Clozapine 178
AIMS and Metabolic Monitoring 182
Chapter 8: The Social Dimensions of Antipsychotics 186
Deinstitutionalization 187
Antipsychotics and the Doctor-Patient Relationship 191
Legal and Ethical Implications of Antipsychotics 195
Antipsychotics and Political Dissent 201
Antipsychotics and the Elderly 202
Antipsychotics and Children 203
When to Treat? The Implications of the Initiation of Antipsychotic Treatment 205
The Business of Antipsychotics 206
Mental Illness and Violence 207
Chapter 9: The Future of Antipsychotics 210
Where Are Antipsychotics Failing? 211
Pathophysiology of Chronic Psychotic Disorders 215
New Medications on the Horizon 217
Better Routes of Administration 222
Use in Nonpsychotic Disorders 228
Directory of Resources 234
Glossary 238
Bibliography 244
Index 248
About the Authors 252

The problem of serious mental illness is a widely discussed topic in the media and popular culture. This text provides a comprehensive analysis of antipsychotic medications, covering historical, social, and scientific viewpoints on this important and controversial class of medications.
Antipsychotics are unique drugs with the ability to alter how people think and communicate. As a result, physicians must weigh a range of implications when prescribing antipsychotics. History, Science, and Issues offers a robust explanation of antipsychotic medications that covers the historical, ethical, medical, legal, and scientific dimensions of antipsychotics.
The chapters explore topics ranging from the science of how examples of this class of drug actually work in the body to the social and legal implications of antipsychotics, making this subject understandable and relatable for lay readers who are not mental health practitioners. Readers will learn why prescribing antipsychotics is often a difficult decision due to the inherent risks of giving these medications to different types of patients and appreciate how mental health laws impact psychiatrists' prescribing practices.

Antipsychotics are unique drugs with the ability to alter how people think and communicate. As a result, physicians must weigh a range of implications when prescribing antipsychotics. Antipsychotics: History, Science, and Issues offers a robust explanation of antipsychotic medications that covers the historical, ethical, medical, legal, and scientific dimensions of antipsychotics. The chapters explore topics ranging from the science of how examples of this class of drug actually work in the body to the social and legal implications of antipsychotics, making this subject understandable and relatable for lay readers who are not mental health practitioners. Readers will learn why prescribing antipsychotics is often a difficult decision due to the inherent risks of giving these medications to different types of patients and appreciate how mental health laws impact psychiatrists' prescribing practices.

"This text provides a comprehensive analysis of antipsychotic medications, covering historical, social, and scientific viewpoints on this important and controversial class of medications. Covers the class of antipsychotic medications in whole, addressing topics ranging from the medications' history and the science of how they actually work in the body to the social and legal implications of antipsychotics; Provides readers with a holistic understanding of an increasingly important class of medications in an accessible format; Presents an unbiased perspective on a class of medications that has been subject to controversy; Serves both as an authoritative reference book for students and as a useful source of practical information that will appeal to a general adult audience"--Provided by publisher

2025-10-27