Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.
* Methodological methods in crystals
* Methodological methods data analysis

lgrsnf/A:\sciencedirect_books\00766879-368 (22).pdf

nexusstc/Macromolecular Crystallography, Part C/4ba44a7c0130c664bf017d51dda4fc38.pdf

zlib/Medicine/Charles W. Carter, Jr. and Robert M. Sweet (Eds.)/Macromolecular Crystallography, Part C_2274235.pdf

edited by Charles W. Carter, Jr., Robert M. Sweet

Charles W. Carter; Robert Mahlon Sweet

Carter, Jr., Charles W.

Jr., Charles W. Carter

Academic Press, Incorporated

Morgan Kaufmann Publishers

Brooks/Cole

Methods in enzymology -- v. 368., San Diego, California, 2003

Methods in enzymology, San Diego, ©1997-2003

United States, United States of America

San Diego, CA, United States, 2004

December 5, 2003

lg1105320

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Includes bibliographical references and indexes.

Content:
Editors In Chief
Page ii
Contributors to VOlume 368
Pages vii-viii
Preface
Pages ix-x
Methods In Enzymology
Pages xi-xxxii
Transformations in Structural Biology: A Personal View Original Research Article
Pages 3-11
Brian W Matthews
Origins Original Research Article
Pages 11-21
Michael G Rossmann
Personal X-ray Reflections Original Research Article
Pages 21-42
U.W. Arndt
Robotics for Automated Crystal Formation and Analysis Original Research Article
Pages 45-76
Mark Weselak, Marianne G Patch, Thomas L Selby, Gunther Knebel, Raymond C Stevens
Use of Limited Proteolysis to Identify Protein Domains Suitable for Structural Analysis Original Research Article
Pages 77-84
Chris M Koth, Stephen M Orlicky, Stephan M Larson, Aled M Edwards
Solvent Entropy Effects in the Formation of Protein Solid Phases Original Research Article
Pages 84-105
Peter G Vekilov
Controlling Biomolecular Crystallization by Understanding the Distinct Effects of PEGs and Salts on Solubility Original Research Article
Pages 105-129
Stéphanie Finet, Denis Vivarès, Françoise Bonneté, Annette Tardieu
Counterdiffusion Methods for Macromolecular Crystallization Original Research Article
Pages 130-154
Juan Ma GarcГ­a-Ruiz
Growth Sectors and Crystal Quality Original Research Article
Pages 154-169
Marie-Claire Robert, Bernard Capelle, Bernard Lorber
Molecular Mechanisms of Defect Formation Original Research Article
Pages 170-188
Peter G Vekilov
Cryocooling of Macromolecular Crystals: Optimization Methods Original Research Article
Pages 188-216
Elspeth F Garman, Sylvie DoubliГ©
The Well-Tempered Protein Crystal: Annealing Macromolecular Crystals Original Research Article
Pages 217-235
B Leif Hanson, Joel M Harp, Gerard J Bunick
What Can I Have As a Source of X-ray Synchrotron Radiation? A Primer for Potential Users Original Research Article
Pages 239-254
Michael Hart
Protein Crystal Structure Analysis from High-Resolution X-Ray Powder-Diffraction Data Original Research Article
Pages 254-267
Robert B.Von Dreele
Macromolecular Crystal Quality Original Research Article
Pages 268-288
Edward H Snell, Henry D Bellamy, Gloria E.O Borgstahl
Protein Structures at Atomic Resolution Original Research Article
Pages 288-337
Zbigniew Dauter
Author Index
Pages 339-361
Subject Index
Pages 363-368

2013-12-20