Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others

upload/newsarch_ebooks_2025_10/2017/06/06/CytoskeletonStructureDynamicsFunction17ITAe.pdf

Computational Tools and Databases for the Study and Characterization of Protein Interactions

Advances in Human-Protein Interaction - Interactive and Immersive Molecular Simulations

G-Protein Coupled Receptors Experimental and Computational Approaches

Protein-Protein Interactions - Computational and Experimental Tools

Slow Protein Conformational Change, Allostery and Network Dynamics

Prediction of Protein Interaction Sites Using Mimotope Analysis

Alex Tek; Marc Baaden; Matthieu Chavent; Nicolas Ferey; Olivier Delalande; Patrick Bourdot

Joan Segura; Jose Ramon Blas Pastor; Narcis Fernandez-Fuentes

Amirhossein Sakhteman

Hao Hong

In Tech d.o.o.

Protein-Protein Interactions-Computational and Experimental Tools

Erscheinungsort nicht ermittelbar, 2012

Croatia, Croatia

producers:
Antenna House PDF Output Library 2.6.0 (Linux64)

类型: 图书

丛书名: Protein-Protein Interactions-Computational and Experimental Tools

出版日期: 2012

出版社: IntechOpen

页码: 21

页码: 19

Cover 1
Cytoskeleton: Structure, Dynamics, Function and Disease 2
© 3
Contents 5
Preface 8
Chapter 1 Reorganization of Vegetal Cortex Microtubules and Its Role in Axis Induction in the Early Vertebrate Embryo 10
Chapter 2 Actin-Microtubule Interaction in Plants 40
Chapter 3 Morphological and Functional Aspects of Cytoskeleton of Trypanosomatids 62
Chapter 4 The Interplay between Cytoskeleton and Calcium Dynamics 80
Chapter 5 Role of Band 3 in the Erythrocyte Membrane Structural Changes Under Isotonic and Hypotonic Conditions 96
Chapter 6 Dystrophin–Glycoprotein Complex in Blood Cells 112
Chapter 7 Biophysics of Fish Sperm Flagellar Movement: Present Knowledge and Original Directions 134
Chapter 8 Cytoskeleton Rearrangements during the Execution Phase of Apoptosis 158
Chapter 9 How are Dynamic Microtubules Stably Tethered to Human Chromosomes? 178
Chapter 10 Muscle Fibers Lacking Desmin in the Extraocular Muscles: A Paradigm Shift 202
Chapter 11 The Actomyosin Network and Cellular Motility: A S100A4 Regulatory View into the Process 210
Chapter 12 Intermediate Filaments as a Target of Signaling Mechanisms in Neurotoxicity 238
Chapter 13 Acting on Actin During Bacterial Infection 262
Chapter 14 Heterotrimeric G Proteins and the Regulation of Microtubule Assembly 284
Chapter 15 Novel Insights into the Role of the Cytoskeleton in Cancer 304
Chapter 16 Targeting the Cytoskeleton with Plant-Bioactive Compounds in Cancer Therapy 320
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2024-06-27